Antiviral

The Library was designed with 2D fingerprint similarity search against the reference set of 6,937 biologically active compounds from 33 therapeutically relevant viral assays representing the following species of viruses:

● Avian sarcoma virus
● Bluetongue virus
● Dengue virus
● Human herpesvirus 4 type 2
● Human immunodeficiency virus 1
● Human immunodeficiency virus 2
● Influenza A virus (-Puerto Rico-8-34(H1N1))
● Influenza A virus (A-Puerto Rico-8-34-Mount Sinai(H1N1))
● Influenza A virus (A-Shangdong-9-1993(H3N2))
● Influenza A virus (A-Singapore-1-1957(H2N2))
● Influenza A virus (A-tern-Australia-G70C-1975(H11N9))
● Influenza A virus (A-Tokyo-3-1967(H2N2))
● Influenza B virus (B-Lee-40)
● Influenza B virus (B-Memphis-3-93)
● Influenza B virus (B-Nashville-6-89)
● Influenza B virus (STRAIN B-VICTORIA-3-85)
● Influenza B virus
● Measles virus
● Rous sarcoma virus (strain Schmidt-Ruppin A)
● West Nile virus

Life Chemicals collection was searched for compounds similar to the downloaded dataset using MDL public keys and the Tanimoto similarity cut-off of 90%.

Over 23,100 potential antiviral agents were extracted into Life Chemicals' Antiviral Library.